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Daily Value
Daily Value brings science out of the lab and into daily life. Hosted by Dr. William Wallace, each short, research-driven episode explores how nutrients, supplements, and metabolism influence how we think, move, and age. It’s evidence-based, concise, and designed to make you smarter about what fuels you.
Episodes
72 episodes
A Nutrient Mixture That Tunes Brain Signaling
Nutrients are usually studied in isolation, yet synapses don’t operate that way. This episode examines research showing that coordinated nutritional inputs can reshape synaptic proteins and neural firing patterns (effects that isolated inputs f...
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Episode 76
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9:06
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How One Amino Acid Touches Two Aging Pathways
L-arginine is usually treated as a simple nitric-oxide precursor, a molecule with a narrow vascular role. But across multiple lines of research, it keeps appearing in places it shouldn’t: improving cerebral blood flow in older adults, shifting ...
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9:34
Two Missing Nutrients, Big Brain Consequences
Parkinson’s is often framed as a brain-first disorder, but some of its earliest changes unfold in the gut. This episode unpacks a global metagenomic analysis showing that two surprisingly ordinary microbial compounds, ones most people consume e...
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Episode 74
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11:09
The Nutrient Your Stress System Overuses
A new brain-imaging meta-analysis has uncovered the first consistent biochemical signature across multiple anxiety disorders (a shift in a single molecule that moves in the opposite direction of every major psychiatric condition studied to date...
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Episode 73
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9:51
Magnesium: The ‘Best’ Form Isn’t What You Think Part 2
Magnesium salts are often marketed as if they target specific tissues - i.e., “threonate for the brain,” “glycinate for calm,” “taurate for the heart.” Part 2 breaks down what the evidence actually shows: animal studies demonstrating tissue dif...
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Episode 72
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10:00
Magnesium: The ‘Best’ Form Isn’t What You Think Part 1.
Magnesium supplements are marketed like different compounds with different biological targets - i.e., “for sleep,” “for the brain,” “for stress,” “for energy.” But the foundation of these claims depends on chemistry: how magnesium salts dissolv...
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Episode 71
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9:25
Common Longevity Medication… Performance Killer?
A medication used by millions (including off-label usage for “longevity” purposes) may alter the fundamental pathways responsible for exercise adaptation. This episode reviews new 2025 data showing reduced improvements in vascular insulin sensi...
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8:29
The Mitochondrial “Vitamin” from Interstellar Dust
There’s a molecule that’s been tentatively identified in the same interstellar material that forms stars and planets, yet it also shapes growth, metabolism, and cognition here on Earth. In several mammalian species,Its absence causes deficiency...
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Episode 69
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7:50
Boost Your Serotonin Naturally: The Nutrition Secret
Serotonin is often described as the “happiness molecule,” but its biology tells a larger story. Nearly every step in serotonin’s synthesis and signaling, from the transport of dietary tryptophan to the enzymes that convert it, is influenced by ...
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Episode 68
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11:25
Discovered: an amino acid that helps the gut heal itself
Every few days, your gut rebuilds itself completely - cell by cell, guided by signals we still don’t fully understand. For years, scientists have known that diet can influence this process, but the exact messenger between what we eat and how th...
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7:42
Creatine’s Role in Mitochondria is Bigger Than You Thought
Creatine’s story has been far too small for its biology. Most people still see it as a supplement for strength or cognitive performance, but its most important work happens inside the mitochondria.In this episode, we explore a side of cr...
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Episode 66
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7:34
Polyphenols Are Doing Something No One Expected
In this episode of The Daily Value, we look at new research suggesting that polyphenols might be doing something we never expected — not just acting as antioxidants, but organizing themselves into microscopic structures that can stabilize the v...
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Episode 65
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11:20
Lead Exposure from Protein Supplements Explained
In this episode of The Daily Value, we examine Consumer Reports’ October 2025 findings on lead in protein powders. The investigation tested 23 products and found that more than two-thirds exceeded the organization’s internal lead safet...
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17:03
Coffee: The 2025 Blueprint
October 1st (yesterday) was International Coffee Day. In this episode, we trace coffee’s journey from ancient ritual to modern science. Once a sacred brew in Ethiopia and Yemen, coffee now fuels billions daily. In 2025, research is rewriting ho...
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9:27
Women and Alzheimer’s: A New Lead
Why are nearly two-thirds of Alzheimer’s patients women? For decades, the explanation seemed simple: women live longer. But the numbers don’t add up. Even after 80, when survival rates even out, women are still more likely to be diagnosed. A ne...
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Episode 62
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13:34
Two Compounds That Recharge Aging Neurons
In the aging brain, neurons begin to lose a hidden currency. Not just ATP, but GTP - that powers their ability to clear away toxic proteins. Without it, the cleanup crews stall, and amyloid builds up. A team at UC Irvine may have uncovered a wa...
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Episode 60
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10:16
The Microbes That Pay Your Energy Bill
Your gut microbes don’t just digest food, they can power you. In this episode, we uncover a hidden energy stream: short-chain fatty acids produced when microbes ferment plant fibers, potentially supplying anywhere from 2% to 10% of your daily c...
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Episode 59
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8:47
Hidden in the Water: Lithium’s Secret
What if one of the brain’s most important defenses was hiding in plain sight? In this episode, we take a look at lithium, a trace element found in water, food, and the brain itself. Long before brain scans, people made pilgrimages to lithium-ri...
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12:22
The Glutathione-Motivation Link
In this episode of Daily Value, we look into the biochemical foundations of motivation, emphasizing the critical role of glutathione, a primary antioxidant in the brain.Motivation is not merely a psychological trait, it is a metabolicall...
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Episode 57
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22:46
The Neuroscience of Dietary Fiber
In this episode of Daily Value, we look at the surprising connection between dietary fiber and cognitive health. Fiber isn’t just about digestion - it’s a powerful nutrient influencing your brain through the gut-brain axis. We’ll take a look at...
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Episode 56
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18:03
Optimizing Vitamin Uptake via the Microbiome
In this episode of Daily Value, we evaluate the often-overlooked yet powerful connection between your gut microbiome and vitamin absorption. Going beyond basic nutrition, we’ll break down how gut bacteria directly influence your body's ability ...
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Episode 55
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11:25
Methylene Blue and the Bioenergetics of Memory
In this episode of Daily Value, we look at the neurometabolic potential of methylene blue, a synthetic dye first synthesized in the 19th century, for supporting brain energy metabolism during aging. Originally developed for textile use, methyle...
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Episode 54
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19:24
The Vitamin C-risis: Why Current Guidelines Fail Us
Today’s episode of Daily Value questions something fundamental—the guidelines that shape our daily vitamin C intake. What if the rules you've been following were set too low, missing a hidden metabolic reality that affects millions? New evidenc...
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Episode 53
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20:46
The Vitamin Link to Neuropsychiatric Disorders
In this episode of Daily Value, we look at the influence of B vitamins on mental health and neuropsychiatric disorders. The discussion is centered around a recently published meta-analysis suggesting a causal link between B vitamin deficiencies...
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Episode 52
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10:06